Gene Editing Just Saved a Baby's Life. (CRISPR Explained)

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A newborn. A diagnosis affecting roughly 1 in 1.3 million babies. And a personalized gene-editing therapy designed in about six months. “What if I told you that gene editing can save your life?” Emma Waters explores the restorative side of gene editing and asks where the line sits between healing and enhancement. 👉 Subscribe so you don’t miss the next episode. CHAPTERS 0:00 Gene Editing That Heals, Not Enhances 1:46 Baby KJ: A Rare Diagnosis and No Time to Wait 4:37 Biology 101: How DNA, CRISPR, and Base Editing Work 6:46 Somatic vs. Germline Editing: Why the Difference Matters 8:17 How Doctors Built KJ’s Personalized Therapy in Six Months 10:13 Germline Editing, U.S. Law, and the 2018 Gene-Edited Twins 13:00 He Jiankui Today and the Debate Over Editing Embryos 14:14 Why Somatic Editing Is Closing the Gap 15:27 Where Is the Line? Restoration vs. Enhancement 17:46 Stewarding Gene Editing With Discernment and Hope DIVE INTO RETHINKING FERTILITY 🔗 Follow, Watch, Listen: linktr.ee/rethinkingfertility 👉 Subscribe and hit the bell so you don't miss next week's episode. SHOW NOTES & SOURCES • Musunuru et al., “Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease,” NEJM 2025: https://www.nejm.org/doi/full/10.1056/NEJMoa2504747 • Children’s Hospital of Philadelphia, first personalized CRISPR therapy (May 2025): https://www.chop.edu/news/worlds-first-patient-treated-personalized-crispr-gene-editing-therapy-childrens-hospital • CHOP one-year anniversary update (Feb 2026): https://www.chop.edu/news/childrens-hospital-philadelphia-marks-one-year-anniversary-worlds-first-personalized-crispr • Gaudelli et al., “Programmable base editing of A-T to G-C,” Nature 2017: https://www.nature.com/articles/nature24644 • Consolidated Appropriations Act, FY2026, Sec. 734 (heritable editing rider): https://www.govinfo.gov/content/pkg/BILLS-119hr5371enr/html/BILLS-119hr5371enr.htm • ARM, ASGCT and ISCT call for a 10-year moratorium on heritable genome editing (May 2025): https://alliancerm.org/press-release/moratorium-on-hhge • AP on the 2018 gene-edited twins: https://www.pbs.org/newshour/science/chinese-researcher-claims-he-created-first-gene-edited-babies • WIRED on He Jiankui (Jan 2026): https://www.wired.com/story/china-he-jiankui-gene-editing-alzheimers/ • Allen, “Growth hormone therapy for short stature,” Pediatrics 2006: https://pmc.ncbi.nlm.nih.gov/articles/PMC2898102 Rethinking Fertility, hosted by policy expert Emma Waters, equips families with honest, evidence‑based education on reproductive technology — grounded in science and a biblical understanding of what it means to be human in an age of limitless medical possibility. #RethinkingFertility #Infertility #ReproductiveTechnology #ReproductiveHealth #GeneEditing

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